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KMID : 0363220140520020129
Korean Journal of Dermatology
2014 Volume.52 No. 2 p.129 ~ p.132
Papular Xanthoma in a Child
Seo Ji-Young

Shin Moon-Seub
Kim Soo-Jin
Haw Sik
Kim Seong-Hyun
Abstract
Papular xanthoma is a rare normolipemic xanthomatous skin disease that primarily occurs in adults. While this rare disorder has been documented in children before, all but one case reported in the literature involved a normal lipid profile. The skin lesions of adult papular xanthoma appear to be persistent, whereas in children they generally self-heal within 1¡­5 years. Here, we describe a typical case of papular xanthoma in a 22-month-old boy who presented with numerous reddish-yellow papulonodules, 2¡­8 mm in diameter, mainly on the face, but also on the upper and lower extremities, and trunk, for 15 months. The lipid profile was normal, and histological studies showed a diffuse monomorphous infiltrate of foamy cells, with some Touton giant cells, in the dermis. The foamy cells stained positive for Cluster of Differentiation (CD) 68, and the Periodic Acid Schiff (PAS) stain was negative. These findings are consistent with the diagnosis of papular xanthoma.
KEYWORD
Children, Papular xanthoma
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